Portable and miniature mass spectrometer for forensic analysis

Tuesday, March 19, 2019


Prakash Khanal

Department of Chemistry

Mississippi State University

When: 03/19 at 4:00PM

Where: Hand 1144

Abstract:

Rapid and on-site chemical analysis to monitor crime scenes and prohibited substances is a demanding issue. This has led to the advent of various analytical tools to facilitate rapid on-site screening. Among various analytical methods, mass spectrometry is well-known for its robustness, accuracy, and reproducibility. Recently, portable and miniaturized mass spectrometers have emerged as a potential technique for field-deployed quantification and identification of chemical substances. Field-deployed mass spectrometry is additionally advantageous for national security, real-time sample analysis, and on-site evidence collection for judicial purposes. Furthermore, the recent development of ambient ionization techniques (i.e. desorption electrospray ionization (DESI), paper spray, touch spray, and direct analysis in real time (DART)) has enabled minimal sample preparation and improved detection limits. These ambient ionization techniques coupled with miniature mass spectrometers allows on-site chemical analysis of compounds in native state. While sample analysis, via portable MS, is both facile and rapid there still exist limitations compared to bench top laboratory based mass spectrometers. This presentation aims to provide insight regarding recent developments in ionization techniques for portable mass spectrometers and their application in forensic science.


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